Regulatory news and experts insights.

Calculating Margins of Safety (MoS) is at the core of cosmetic ingredient safety assessment. On paper, the principle appears simple: comparing a no-effect dose to an estimated exposure in order to verify that a sufficient safety margin exists. In practice, however, things are often far more complex.

The adoption of Directive (EU) 2024/3019 on urban wastewater treatment (UWWTD), published on 12 December 2024, introduces unprecedented requirements for the pharmaceutical industry. Integrated into the EU “Zero Pollution” Action Plan, this legislation imposes stringent management obligations for pharmaceutical residues

CEHTRA is pleased to announce its participation in the SETAC Europe 36th Annual Meeting, taking place from May 19–21, 2026 in Maastricht. During the event, Floriane Demailly and Mylène Léger will present a scientific poster addressing the implementation challenges associated with the new “rapidly biodegradable” criterion introduced under the recast Urban Waste Water Treatment Directive (UWWTD).

La Directive (UE) 2020/2184 introduit une réforme majeure de la sécurité sanitaire des eaux destinées à la consommation humaine. Son Article 11 est le pilier central des exigences minimales d’hygiène applicables aux matériaux en contact avec l’eau, visant à garantir que ces derniers ne compromettent pas la santé humaine, n'altèrent pas les propriétés organoleptiques de l'eau (notamment le goût, l’odeur ou la couleur) et ne favorisent pas la croissance microbienne.

In today’s organisations, ensuring effective regulatory and toxicological monitoring of chemical substances has become a major challenge for regulatory teams, toxicologists, and R&D departments.