ED Pedia: Your tool
to identify Endocrine Disruptors (EDs)

In the European Union, an endocrine disruptor is defined as a substance that interferes with the hormonal system, potentially causing adverse effects on humans and wildlife. These substances can be synthetic or natural and can affect reproduction, growth and development.

In Europe, endocrine disruptors are assessed through various regulations, including those relating to pesticides and biocides and they can be classified according to CLP.

EFSA and ECHA have published a guidance and OECD has edited a guideline to help identify these substances.

The criteria for identifying a substance as an endocrine disruptor are as follows:

1. Endocrine activity: the substance must have endocrine activity.

2. Adverse health effect: it must produce an adverse health effect.

3. Plausible biological link: there must be a plausible biological link between the endocrine activity and the adverse effect.

ED Pedia searches for CAS Numbers in lists from hazard assessment programs that identify potential Endocrine Disruptors, with different levels of concern. For a specific CAS Number, ED Pedia reports for each of the lists whether or not the substance is included.

Results, especially those describing the outcome of ED evaluation other than by the relevant authorities should be taken with care, as CEHTRA – though delivering its best efforts - is not responsible and shall not be held liable for the content of the lists.

The easiest way to check if a substance may have endocrine-disrupting (ED) properties is by searching its CAS number in official regulatory lists. ED Pedia allows you to instantly screen substances against hazard assessment programs, download a PDF report, and access expert guidance to interpret the results. This helps stakeholders save time, ensure compliance, and make reliable decisions.

If you need help in the interpretation of the results given by the tool, don’t hesitate to contact our expert: Julien Leghait