How likely is it for my substance to be an Endocrine Disruptor ?
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What is ED Pedia?
ED Pedia allows any stakeholder of a substance
(a) to check instantaneously whether this substance likely has, or not, ED properties,
(b) to access instantaneously to the relevant documentation,
(c) to download a PDF report on the findings and
(d) if needed, to access CEHTRA expert advice to draw conclusions from the report.
What is an Endocrine Disruptor?
According to the WHO definition 2002, an Endocrine Disruptor (ED) is 'an exogenous substance or mixture that alters function(s) of the endocrine system and consequently causes adverse effects in an intact organism, or its progeny, or (sub)populations'.
This definition is used to identify Substances of Very High Concern (“SVHC”) for human health and/or the environment due to their endocrine disrupting properties under the REACh (Registration, Evaluation, Authorization and restriction of Chemicals) legislation (European Parliament and Council of the European Union, 2006).
A definition of endocrine disruptors for substances in plant protection and biocidal products was adopted in 2017 at European level (EU Regulations 2017/2100 and 2018/605) (European Commission, 2017, 2018).
In 2018, a guidance document was published by the European Food Safety Authority (EFSA) for the identification of endocrine disruptors (EFSA, 2018). Several other agencies and public programs also focus on this issue.
How does ED Pedia work?
ED Pedia searches for CAS Numbers in lists yield from hazard assessment programs that identify potential Endocrine Disruptors, with different levels of concern.
For a specific Substance CAS Number, ED Pedia reports for each of the lists whether or not the substance is included.
Results, especially those describing the outcome of ED evaluation by the relevant authorities should be taken with care, as CEHTRA – though delivering its best efforts - is not responsible and shall not be held liable for the content of the lists.
Useful information for ED Pedia users