The use of any new cosmetic ingredient must be safe. That is a legal obligation according to Article 3 of the European Cosmetic Regulation and in other cosmetic-related laws and standards throughout the world, but also a moral one, as it would be unethical to place on the market a substance that is toxic, or whose toxicity is unknown and for which safe exposure cannot be demonstrated.

COSMETICK is a toxicological and ecotoxicological profile database, combined with a digital cosmetic risk assessment tool. It is designed to support toxicologists and safety assessors in the preparation of Cosmetic Product Safety Reports (CPSR), as well as in the safety assessment of ingredients, impurities, raw materials and fragrance compounds or fragrance concentrates.

L'apparition inattendue d'impuretés de N-nitrosamines dans les médicaments a marqué un tournant réglementaire majeur. Ces composés, connus dans l'environnement et l'alimentation, ont forcé l'industrie pharmaceutique mondiale à revoir ses processus. Face à cette situation, une coordination internationale sans précédent a vu le jour entre les agences réglementaires mondiales, telles que la FDA (États-Unis),